This is the most common concern. Some boiler manufacturers have historically stated that their warranty is conditional on water quality. The position has evolved: most major UK boiler manufacturers (Vaillant, Worcester Bosch, Baxi, Ideal) now explicitly accept the use of water softeners and do not consider softened water grounds for warranty invalidation.
Critically: the relevant regulation is BS 7593, which governs the treatment of water in heating systems. A properly commissioned softener that supplies soft water meeting the BS 7593 specification is fully compatible with all major combi boilers. Confirm this with your boiler manufacturer's technical team if you have any specific concerns about your model.